Characterization of the bZip-type transcription factor NapA with reference to oxidative stress response in Aspergillus nidulans.
نویسندگان
چکیده
Microorganisms growing in natural habitats are constantly confronted with a wide variety of external stresses. Here we provide several lines of experimental evidence for the thesis that the filamentous fungus Aspergillus nidulans has a homolog of the AP-1-like bZip transcription factor, which is known to play general roles in oxidative responses in many types of yeast.
منابع مشابه
NapA Mediates a Redox Regulation of the Antioxidant Response, Carbon Utilization and Development in Aspergillus nidulans
The redox-regulated transcription factors (TFs) of the bZIP AP1 family, such as yeast Yap1 and fission yeast Pap1, are activated by peroxiredoxin proteins (Prxs) to regulate the antioxidant response. Previously, Aspergillus nidulans mutants lacking the Yap1 ortholog NapA have been characterized as sensitive to H2O2 and menadione. Here we study NapA roles in relation to TFs SrrA and AtfA, also i...
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ورودعنوان ژورنال:
- Bioscience, biotechnology, and biochemistry
دوره 71 7 شماره
صفحات -
تاریخ انتشار 2007